Collagen Matrix
Supporting Regeneration Naturally

Have you ever wondered how quickly and efficiently the human body heals? One of the most remarkable aspects of the human body is its ability to regenerate tissues. While this capability is unique, several factors can affect the process, and sometimes our bodies need a little help. To this end, effective regenerative treatments play a pivotal role in enhancing the human body’s healing capability. Innovative advancements in the regenerative medicine space often rely on collagen, a structural protein in soft tissue and bones. As the market rewards consistent, high quality, implantable grade collagen material and technology as well as those companies able to navigate regulatory hurdles to ensure effective development and production of collagen-based medical devices that support regeneration, Oakland-based Collagen Matrix is committed to delivering on that promise.

With the perfect blend of manufacturing expertise and proprietary technologies, Collagen Matrix has continued to expand its capabilities as a successful manufacturer and supplier of high-quality collagen-and mineral-based regenerative medical devices for over two decades. “We bring innovation to life by delivering reliable regenerative solutions for clinical applications in areas such as dental, orthopedic, spine, neurosurgery, sports medicine and beyond,” says Shawn McCarthy, Chief Executive Officer, Collagen Matrix. Peggy Hansen, General Manager, Contract Development and Manufacturing, adds, “We’ve expanded into the area of contract development and manufacturing, building upon our foundation of full product life cycle experience and end-to-end supply chain management expertise.”

Collagen Matrix has an entrepreneurial spirit in contract development and manufacturing that stems from its 23-years of industry experience. With a proven track record of customized product development and speed to market, Collagen Matrix is extending contract development and manufacturing services, making outsourcing a viable option for med-tech companies searching for technical expertise and pace of execution.

Collagen Matrix’s core competence of managing the supply and processing of animal-sourced collagen materials and global regulatory expertise enables contract manufacturing clients to quickly access new product market opportunities on a cost-effective basis.

Collagen Matrix’s regenerative solutions are innovative products that facilitate healing by providing a natural resorbable scaffold for tissue regeneration. The company uses its own proprietary processes for manufacturing. With patent protected advanced tissue regeneration technologies, Collagen Matrix manages device design characteristics to ensure a balance between resorption and regeneration, thereby creating an optimal environment for regeneration.

Collagen Matrix’s client engagement begins with a review of the product concept and needs of the specific clinical indication. This is followed by the development phase where the team creates design inputs and performs characterization tests on the material to ensure the quality exceeds ASTM standards and that the product meets customer needs. Once the client receives prototype validation from their end users, the Collagen Matrix team moves forward with design transfer, process validation and produces commercial-ready products. On-going contract manufacturing of the product is then performed under FDA and ISO quality system standards. The company also takes on large existing manufacturing processes, particularly those involving collagen-based materials, to facilitate cost efficiencies and reduction in regulatory burden for its clients.

To illustrate the company’s contract manufacturing solutions, Peggy cites an example of a client who approached them after struggling with inconsistent product quality and process validation issues. Collagen Matrix stepped in and provided consistent product quality, efficient product development, and process validations. They also helped the client to consolidate their supply chain, ensuring a seamless, cost-effective process from design through sterile final device. With the successful launch of the first product, the client has subsequently entered into further development contracts for line extensions and next generation products.

Collagen Matrix has also launched a new synthetic biomaterials technology to complement its existing collagen offerings for the road ahead. In addition, the company is concentrating on expanding its core platform technologies. “We are looking for partnerships and contract development clients focused on tissue engineering and drug-device combination products, and we’re expanding into new end markets such as cardiovascular and general surgery as well,” concludes Peggy.